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MineralsModerate evidence

Zinc

Also called: zinc gluconate, zinc picolinate, zinc citrate, zinc oxide.

A supporting mineral for immunity and skin, where prolonged high-dose use tips your copper status.

What it is

Zinc takes part in the activity of a large number of enzymes, in immune function, protein synthesis and wound repair. The recommended intake for adults is 11 mg per day for men and 8 mg for women. It is sold mostly for immunity, skin and the hormonal side.

What the label does not say

  • The NIH specifies that the nutrition facts table declares elemental zinc, not the weight of the whole compound. A zinc gluconate listed at 50 mg of salt does not provide 50 mg of zinc.
  • From about 50 mg per day for a few weeks, the NIH reports inhibited copper absorption, reduced immune function and lower HDL cholesterol. That is the opposite of the effect you are after.
  • The upper limit of 40 mg per day applies to total intake. A dedicated supplement, a multivitamin and lozenges add up without the total appearing anywhere.

The forms on the shelf

  • Gluconate and citrate: the NIH reports absorption of about 61% in young adults.
  • Oxide: absorption of about 50% in the same NIH comparison.
  • Picolinate: heavily promoted on store shelves, but the NIH fact sheet does not set it apart from the other salts on absorption.

Published reference values

  • Recommended intake for adults: 11 mg per day for men, 8 mg for women.
  • Upper limit: 40 mg per day for adults, all sources combined.
  • Above that, the NIH reports nausea, dizziness, headaches, stomach discomfort, vomiting and loss of appetite.

When

Often taken with a meal to limit nausea. Spacing it from certain antibiotics matters more than the time of day.

Keep apart from

  • Quinolones and tetracyclines: at least 2 hours before or 4 to 6 hours after.
  • Penicillamine: at least 1 hour apart.

To mention to a professional

  • Prolonged use above 40 mg per day and copper status, use of thiazide diuretics (which increase urinary zinc excretion), pregnancy and breastfeeding: check with a health care professional.

From the plate first

Oysters provide about 32 mg per 3 ounces according to the NIH. Beef, crab, pork, turkey, pumpkin seeds and fortified cereals provide it too. Zinc from legumes and whole grains is less well absorbed.

Sources

Educational information, drawn from the sources above. It does not replace the advice of a health professional, who remains the reference for your situation, your medications, pregnancy or breastfeeding.

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