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Protein powder: whey, casein, plant-based

Also called: whey, whey protein concentrate (WPC), whey protein isolate (WPI), hydrolysate, micellar casein, pea, rice, soy protein, mass gainer.

A dehydrated food more than a supplement: what counts is the day's total, the leucine and what the label does not measure.

What it is

A protein powder is a dietary protein isolated from milk (whey, casein), egg or plants (pea, rice, soy, hemp), dried and flavoured. It provides the same amino acids as a meal, faster and without the rest. The ISSN (International Society of Sports Nutrition) describes supplementation as a practical way to reach the desired quantity and quality, not as superior to whole foods. People buy it for muscle mass, recovery and satiety.

What the label does not say

  • It is the day's total that counts, not the hour: the Morton meta-analysis (49 trials, 1,863 participants) finds a plateau in lean mass gains at about 1.62 g/kg per day (95% CI 1.03 to 2.20), and the ISSN reports that the effect of timing nearly disappears once total intake is accounted for, with heightened sensitivity extending over the 5 to 6 hours after exercise. The 30-minute "anabolic window" is a store-shelf argument.
  • The protein figure on the label comes from a nitrogen measurement: the reference method (Kjeldahl) assays total nitrogen and multiplies it by a factor, and any non-protein nitrogen, including free amino acids, is counted as protein. That is the loophole exploited by adding cheap amino acids (glycine, taurine, creatine), known as "protein spiking"; no peer-reviewed quantification was found, but an analysis of 47 whey powders on the European market measured 70.9% protein on average versus 74.3% declared, with extremes of 18 to 92.3%. Added free amino acids appear only in the ingredient list.
  • Plant-based does not mean equivalent: at an equal dose, leucine and essential amino acids are lower, and the ISSN suggests a larger dose or a blend (pea and rice, for example) to reach the 700 to 3,000 mg of leucine per serving; 48 g per day of rice protein gave gains similar to whey in trained people. Soy is complete (PDCAAS of 1.0 according to Hoffman and Falvo) but Health Canada caps it at 35 g per day.
  • Heavy metals: a 2020 risk assessment based on published analyses concludes that exposure to arsenic, cadmium, mercury and lead through these powders does not exceed risk thresholds (hazard index below 1), with mass gainer powders the most loaded and wheys the least. Commercial laboratory reports relayed by the media were not retained.

The forms on the shelf

  • Whey concentrate: 29 to 80% protein by dry weight according to the ISSN, the rest being mostly lactose and fat.
  • Whey isolate: more than 90% protein, with lactose and fat largely removed by ion exchange or microfiltration, which makes it usable by people who are lactose intolerant according to Hoffman and Falvo.
  • Hydrolysate: protein pre-digested into di-, tri- and tetrapeptides; the ISSN does not separate its results from those of the isolate. Casein: clots in the stomach and digests more slowly; 30 to 40 g before bedtime increase overnight protein synthesis (ISSN).
  • Plant-based (pea, rice, soy, hemp): essential amino acids at 26 ± 2% of the protein versus 37 ± 2% for animal proteins, lower leucine (5.1% for hemp versus 11% for whey), with lysine and methionine often limiting (Gorissen 2018).

Published reference values

  • ISSN: 1.4 to 2.0 g/kg per day for most people who train; 0.25 g/kg or 20 to 40 g per serving, with 700 to 3,000 mg of leucine, every 3 to 4 hours. Morton: gains attributable to the supplement of 0.30 kg of lean mass and 2.49 kg of strength (1RM) over the length of a program, smaller with age.
  • Health Canada (Workout Supplements monograph): up to 90 g per day of proteins and amino acids; above 30 g per day, the statements "consult if you have a liver or kidney disorder" and "gastrointestinal discomfort possible".
  • Kidney: the Devries meta-analysis (28 trials, 1,358 healthy adults) finds no difference in the change in glomerular filtration rate between high and normal protein intakes. The Australian Institute of Sport classes isolated protein among the sports foods in its Group A.

When

Any time of day, aiming for the daily total split into 3 to 4 servings; after training remains practical, not mandatory. Casein finds its place before bedtime.

Keep apart from

  • Medications and other health products: Health Canada asks you to take protein products a few hours before or after, without quantifying the interval.

To mention to a professional

  • Liver or kidney disorder, allergy to milk proteins or soy, lactose intolerance (the isolate contains little), pregnancy and breastfeeding: check with a health care professional.

From the plate first

A chicken breast, a Greek yogurt, eggs or lentils do the same job with the micronutrients on top; the ISSN points out that an active person can meet their needs with whole foods.

Sources

Educational information, drawn from the sources above. It does not replace the advice of a health professional, who remains the reference for your situation, your medications, pregnancy or breastfeeding.

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